Fredy curled a superb set-piece onto the post as Angola and Egypt played out a draw.
Liverpool star Mohamed Salah and Etihad counterpart Omar Marmoush remained unused substitutes as the group leaders Egypt were held to a draw with Angola at the Afcon 2025.
The record winners, having clinched top spot, fielded an completely rotated starting XI and lacked a clinical finish in the Moroccan city.
Angola, who needed a victory to keep their hopes alive, will now endure an anxious period to see if their two points is sufficient to advance for the knockout stage as one of the four best-placed third-place teams.
Benin, Sudan and Mozambique are assured of at least third place in their respective groups, all having three points.
Attacker Fredy rattled the outside of a post for Angola early in the second half, while Zizo – one of three halftime changes by the Pharaohs – stung goalkeeper Hugo Marques' palms with a effort from inside the box.
Salah and Marmoush had previously found the net in comeback wins over Zimbabwe and South Africa, in turn.
Egypt will stay in Agadir to meet a runner-up from another group next Monday, with their opponents to be confirmed after the preliminary round finishes on Wednesday.
In the other Group B closer, South Africa's 3-2 win over Zimbabwe sent Bafana Bafana through automatically, leaving Angola in a precarious position.
Mohamed Salah watched Egypt fail to score in an Afcon match for the first occasion since the 2021 final.
With top spot secured, Egypt coach Hossam Hassan might have hoped for a more impressive attacking performance from his second string.
Mostafa Mohamed, who netted four goals at the previous tournament, created an first-half chance for Hossam Abdelmaguid, but the defender looped his header wide of the target.
Angola, making seven changes themselves, nearly went ahead when Chico Banza combined with Mabululu before dragging a shot past the post.
The first half ended without a shot on target, though Fredy forced goalkeeper Mostafa Shobeir into action with a powerful long-range attempt.
The Angolan captain was the likeliest threat, seeing a free-kick elude the goalkeeper but crash against the woodwork.
At the other end, Salah Mohsen was stunned after almost tapping in a cross, only for the goal to be flagged offside.
Late attempts from M'Bala Nzola and Hamdi Fathy could not break the deadlock, ensuring the match ended scoreless.
For Angola, quarter-finalists in 2023, their disjointed performances in Morocco will lead to scrutiny about their mid-tournament managerial change.
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